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还原肟和腙:不对称和非对映选择性方法,Current Organic Chemistry

秘境掉落 2025-12-03 02:26:24
The asymmetric reduction of oximes and hydrazones is an attractive and versatile strategy for the synthesis of chiral amines, which are valuable building blocks in organic synthesis. This re...

The asymmetric reduction of oximes and hydrazones is an attractive and versatile strategy for the synthesis of chiral amines, which are valuable building blocks in organic synthesis. This review summarizes the relevant developments made in the last decade on the enantioselective and diastereoselective reduction of oximes and hydrazones involving metalcatalyzed hydrogenation/hydrogenolysis reactions, hydride donor reactions, and electrochemical reactions.